General Question for the Week of April 22, 2024


If a patient has rheumatoid arthritis and comes in for a methotrexate injection, do we use the chemotherapy injection code?


Yes, if we look at the guidelines for chemotherapy administration in the CPT® book they specifically reference that for some drugs we will utilize that series of CPT® codes for the administration and treatment of non-cancer diagnoses. It is dependent upon the drug and the qualification of that highly-complex drug or that it is defined as an anti-neoplastic. So, for this question, yes, the methotrexate is going to be coded with a chemotherapy injection code.

This question was answered in our annual Hospital Outpatient Infusion Services: Reimbursement & Compliance Update webcast. For more hot topics relating to infusion services, please visit our store or call us at 1.800.252.1578, ext. 2.

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