General Question for the Week of February 6, 2023


Can you tell me more about the guidelines for how CART-T infusion is administered and performed?


The physician or other qualified health care professional evaluates the patient immediately before the autologous CAR-T infusion and monitors multiple physiologic parameters, including frequent monitoring of vital signs and clinical status. The physician or other qualified health care professional, nurse, and cell-processing technologist review the cell-product label, patient identification, sterility testing, and product characteristics. The physician or other qualified healthcare professional is present for 15 to 30 minutes (this can occur over a longer period of time depending on infusion rate) to supervise the initiation of the product infusion and is immediately available to manage toxicities and complications occurring during and immediately following the infusion.


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