Laboratory Question for the Week of September 18, 2023


Which code should we use to perform semi/quantitative methods vs. manual methods for in situ


Semi/quantitative in situ hybridization (tissue or cellular) performed by computer-assisted technology should be reported as 88367, +88373, or 88374 when performed by a physician. Manual methods should be reported with codes 88368, +88369, or 88377. Refer to the latest NCCI policy manual for instruction on reporting in situ hybridization by non-physician staff and in conjunction with other procedures.

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