Laboratory Question for the Week of February 7, 2022

Question:

Why were codes 81228 and 81229 revised in 2022?

Answer:

Codes 81228 and 81229 were revised to encompass all common elements of cytogenomic analysis and to pave the way for new code 81349. These codes may not be reported in conjunction with each other nor with new code 81349.

81228 Cytogenomic (genome-wide) analysis for constitutional chromosomal abnormalities; interrogation of genomic regions for copy number variants, comparative genomic hybridization [CGH] microarray analysis
81229 Cytogenomic (genome-wide) analysis for constitutional chromosomal abnormalities; interrogation of genomic regions for copy number and single nucleotide polymorphism (SNP) variants, comparative genomic hybridization (CGH) microarray analysis

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